If you struggle with fatigue - you are stressed, anxious, or have trouble with concentration, poor memory, thyroid issues, losing weight, you may have Adrenal Fatigue. This is one of the most common health issues. Adrenal fatigue is still not diagnosed by most doctors until it becomes Addison's disease, the last stage of adrenal fatigue. Most fatigue problems and adrenal insufficiency come from issues with the adrenal glands.